Mass Spectrometry is a peer-reviewed, open access journal publishing articles in all areas of mass spectrometry. Published continuously online, the journal is fully indexed in J-STAGE and PubMed Central.
Mass Spectrometry welcomes submissions from around the world.
About the journal
Mass Spectrometry is an academic journal on both fundamentals and applications of mass spectrometry, owned and published by the Mass Spectrometry Society of Japan (MSSJ).
Readers
Anyone may access all articles in Mass Spectrometry from J-STAGE and PMC.
Contact
This site is operated by the Mass Spectrometry Society of Japan.
The Mass Spectrometry Society of Japan
c/o Academy Center, Yamabuki-cho 358-5, Shinjuku-ku, Tokyo 162-0801, Japan
TEL: +81-3-6824-9378
E-mail: mssj-post[at]as.bunken.co.jp
(Note : change [at] to @ when typing in address.）
Latest articles
Original ArticleFebruary 19, 2026
Interpretation of α-Pinene Mass Spectra in APCI-Like Ambient Mass Spectrometry Using GC-Coupled Atmospheric Pressure Corona Discharge Ionization
Ren Ishihara, Daisuke Fukuyama, Kanako Sekimoto
Ambient mass spectrometry (AMS) enables real-time analysis without sample preparation, yet atmospheric pressure corona discharge ionization (APCI)-like ion sources can oxidize analytes in-source, obscuring spectral interpretation.
Original ArticleFebruary 10, 2026
Evaluation of LC/MS Methods for Hydrophilic Metabolites to Enable Integration of Human Blood Metabolome Data
Yuri Imado, Masatomo Takahashi, Yuki Soma, Shunsuke Aburaya, Kohta Nakatani, Taizo Hanai, Takeshi Bamba, Yoshihiro Izumi
Information on candidate biomarker metabolites identified in recent disease biomarker discovery research is expected to play a key role in the future of personalized and precision medicine.
Technical ReportFebruary 4, 2026
High Recovery Stop-and-Go Extraction Tips Using Polytetrafluoroethylene Disks Embedded with Poly(styrene-divinylbenzene) Particles for Proteomics
Hiroto Kakiuchi, Eisuke Kanao, Kosuke Ogata, Yasushi Ishihama
The stop-and-go extraction tip (StageTip) is widely used for peptide purification in bottom-up proteomics, yet the original 3M Empore disk is no longer available, prompting the need to evaluate current alternatives. Two types of commercially available poly(styrene-divinylbenzene) (SDB)-containing polytetrafluoroethylene (PTFE) disks were used to fabricate StageTips.
Featured articles
Original ArticleJuly 17, 2024
Direct ESI-MS of Ionic Liquids Using High-Pressure Electrospray From Large-Bore Emitters Made of Micropipette Tips
Takeshi Matsuda, Lee Chuin Chen
Electrospray ionization mass spectrometry of neat undiluted ionic liquid (IL) and the analysis of protein with the doping of IL were performed using high-pressure electrospray. The use of disposable micropipette tips as emitters eased the handling of viscous and easy-to-clog samples and improved the reproducibility of the measurement.
Original ArticleDecember 29, 2024
Atmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparation
Riku Hirotani, Yuto Miyoshi, Varun Sendilraj, Hisanao Hazama
Mass spectrometry (MS) is a valuable tool that enables label-free analysis and the ability to measure multiple molecules. The atmospheric pressure MS imaging (MSI) method usually requires tedious sample preparation.
Original ArticleApril 11, 2023
Comprehensive Membrane N-Glycoproteomics Using Human Breast Cancer Cell Line Pairs
Daisuke Takakura, Haruka Yoshida, Shoko Ohashi, Nana Kawasaki
Aberrant glycosylation of membrane proteins is a hallmark of cancer and a useful molecular marker for the diagnosis of breast cancer (BC). However, the molecular mechanisms by which altered glycosylation affects the malignant transformations associated with BC are poorly understood. Accordingly, we performed comparative
